Homologous recombination and nonhomologous end-joining repair pathways regulate fragile site stability

Common fragile sites are specific loci that form gaps and constrictions on metaphase chromosomes exposed to replication stress, which slows DNA replication. These sites have a role in chromosomal rearrangements in tumors; however, the molecular mechanism of their expression is unclear. Here we show...

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Bibliographische Detailangaben
Hauptverfasser: Schwartz, Michal, Zlotorynski, Eitan, Goldberg, Michal, Ozeri, Efrat, Rahat, Ayelet, Sage, Carlos le, Chen, Benjamin P.C., Chen, David J., Agami, Reuven, Kerem, Batsheva
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2005
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1283964/
https://ncbi.nlm.nih.gov/pubmed/16291645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.340905
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