The Polycomb Group Protein EZH2 Impairs DNA Repair in Breast Epithelial Cells

The Polycomb group protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to aggressive and metastatic breast cancer. Here we report that EZH2 decreased the expression of five RAD51 paralog proteins involved in homologous recombination (HR) repair of...

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Main Authors: Zeidler, Michael, Varambally, Sooryanarayana, Cao, Qi, Chinnaiyan, Arul M., Ferguson, David O., Merajver, Sofia D., Kleer, Celina G.
格式: Artigo
語言:Inglês
出版: Neoplasia Press, Inc. 2005
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502020/
https://ncbi.nlm.nih.gov/pubmed/16331887
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