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Noncanonical Functions of the Polycomb Group Protein EZH2 in Breast Cancer
Enhancer of Zeste Homologue 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 (PRC2) that is critical for determining cell identity. An epigenetic writer, EZH2 has a well-defined role in transcriptional repression by depositing trimethyl marks on lysine 27 of histone H3. However...
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| Veröffentlicht in: | Am J Pathol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8127103/ https://ncbi.nlm.nih.gov/pubmed/33556366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2021.01.013 |
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