Repression of E-cadherin by the Polycomb Group Protein EZH2 in Cancer

Enhancer of Zeste Homolog 2 (EZH2) is a critical component of the Polycomb Repressive Complex 2 (PRC2), which is involved in gene silencing and histone H3 lysine 27 methylation. EZH2 plays a master regulatory role in controlling such processes as stem cell differentiation, cell proliferation, early...

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Autores principales: Cao, Qi, Yu, Jindan, Dhanasekaran, Saravana M., Kim, Jung H., Mani, Ram-Shankar, Tomlins, Scott A., Mehra, Rohit, Laxman, Bharathi, Cao, Xuhong, Yu, Jianjun, Kleer, Celina G., Varambally, Sooryanarayana, Chinnaiyan, Arul M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2690514/
https://ncbi.nlm.nih.gov/pubmed/18806826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.333
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