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The Polycomb Group Protein EZH2 Impairs DNA Repair in Breast Epithelial Cells

The Polycomb group protein EZH2 is a transcriptional repressor involved in controlling cellular memory and has been linked to aggressive and metastatic breast cancer. Here we report that EZH2 decreased the expression of five RAD51 paralog proteins involved in homologous recombination (HR) repair of...

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Detalhes bibliográficos
Main Authors: Zeidler, Michael, Varambally, Sooryanarayana, Cao, Qi, Chinnaiyan, Arul M., Ferguson, David O., Merajver, Sofia D., Kleer, Celina G.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press, Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502020/
https://ncbi.nlm.nih.gov/pubmed/16331887
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