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Targeted Overexpression of EZH2 in the Mammary Gland Disrupts Ductal Morphogenesis and Causes Epithelial Hyperplasia

The Polycomb group protein enhancer of zeste homolog 2 (EZH2), which has roles during development of numerous tissues, is a critical regulator of cell type identity. Overexpression of EZH2 has been detected in invasive breast carcinoma tissue samples and is observed in human breast tissue samples of...

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Autori principali: Li, Xin, Gonzalez, Maria E., Toy, Katherine, Filzen, Tracey, Merajver, Sofia D., Kleer, Celina G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731143/
https://ncbi.nlm.nih.gov/pubmed/19661437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090042
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