The role of minor groove functional groups in DNA hydration
Here we describe the crystal structure of modified [d(CGCGAATTCGCG)](2) refined to 2.04 Å. The modification, which affects only the two thymines at the central ApT step, involves isosteric removal of the 2-keto oxygen atoms and substitution of the N1 nitrogen with carbon. The crystal structure revea...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2003
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12595562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg240 |
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