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The role of minor groove functional groups in DNA hydration
Here we describe the crystal structure of modified [d(CGCGAATTCGCG)](2) refined to 2.04 Å. The modification, which affects only the two thymines at the central ApT step, involves isosteric removal of the 2-keto oxygen atoms and substitution of the N1 nitrogen with carbon. The crystal structure revea...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC149833/ https://ncbi.nlm.nih.gov/pubmed/12595562 |
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