The role of minor groove functional groups in DNA hydration

Here we describe the crystal structure of modified [d(CGCGAATTCGCG)](2) refined to 2.04 Å. The modification, which affects only the two thymines at the central ApT step, involves isosteric removal of the 2-keto oxygen atoms and substitution of the N1 nitrogen with carbon. The crystal structure revea...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Autores principales:	Woods, Kristen Kruger, Lan, Tao, McLaughlin, Larry W., Williams, Loren Dean
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 2003
Materias:	Articles
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC149833/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12595562/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg240
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