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The role of minor groove functional groups in DNA hydration

Here we describe the crystal structure of modified [d(CGCGAATTCGCG)](2) refined to 2.04 Å. The modification, which affects only the two thymines at the central ApT step, involves isosteric removal of the 2-keto oxygen atoms and substitution of the N1 nitrogen with carbon. The crystal structure revea...

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Bibliografiske detaljer
Main Authors: Woods, Kristen Kruger, Lan, Tao, McLaughlin, Larry W., Williams, Loren Dean
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC149833/
https://ncbi.nlm.nih.gov/pubmed/12595562
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