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Exocyclic groups in the minor groove influence the backbone conformation of DNA

Exocyclic groups in the minor groove of DNA modulate the affinity and positioning of nucleic acids to the histone protein. The addition of exocyclic groups decreases the formation of this protein–DNA complex, while their removal increases nucleosome formation. On the other hand, recent theoretical r...

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Autori principali: Wellenzohn, Bernd, Flader, Wolfgang, Winger, Rudolf H., Hallbrucker, Andreas, Mayer, Erwin, Liedl, Klaus R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC97579/
https://ncbi.nlm.nih.gov/pubmed/11812834
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