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Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development
Autotaxin (ATX), or nucleotide pyrophosphatase-phosphodiesterase 2, is a secreted lysophospholipase D that promotes cell migration, metastasis, and angiogenesis. ATX generates lysophosphatidic acid (LPA), a lipid mitogen and motility factor that acts on several G protein-coupled receptors. Here we r...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1489177/ https://ncbi.nlm.nih.gov/pubmed/16782887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02419-05 |
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