A Fluorogenic Phospholipid Substrate to Detect Lysophospholipase D/Autotaxin Activity

[Figure: see text] Lysophospholipase D (lysoPLD), also known as Autotaxin (ATX), is an important source of the potent mitogen lysophosphatidic acid (LPA). Two fluorogenic substrate analogs for lysoPLD were synthesized in nine steps from (S)-PMB-glycerol. The substrates (FS-2 and FS-3) show significa...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Ferguson, Colin G., Bigman, Cleve S., Richardson, Robyn D., van Meeteren, Laurens A., Moolenaar, Wouter H., Prestwich, Glenn D.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528860/
https://ncbi.nlm.nih.gov/pubmed/16671772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol060414i
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares