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A Fluorogenic Phospholipid Substrate to Detect Lysophospholipase D/Autotaxin Activity
[Figure: see text] Lysophospholipase D (lysoPLD), also known as Autotaxin (ATX), is an important source of the potent mitogen lysophosphatidic acid (LPA). Two fluorogenic substrate analogs for lysoPLD were synthesized in nine steps from (S)-PMB-glycerol. The substrates (FS-2 and FS-3) show significa...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2528860/ https://ncbi.nlm.nih.gov/pubmed/16671772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol060414i |
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