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Therapeutic Potential of Autotaxin/Lysophospholipase D Inhibitors
Lysophosphatidic acids are structurally simple lipid phosphate esters with a now widely appreciated role as extracellular signaling molecules. LPA binds to selective cell surface receptors to promote cell growth, survival, motility and differentiation. Studies using LPA receptor knockout mice and ex...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724932/ https://ncbi.nlm.nih.gov/pubmed/18691016 |
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