Autotaxin/Lysopholipase D and Lysophosphatidic Acid Regulate Murine Hemostasis and Thrombosis

The lipid mediator lysophosphatidic acid (LPA) is a potent regulator of vascular cell function in vitro, but its physiologic role in the cardiovasculature is largely unexplored. To address the role of LPA in regulating platelet function and thrombosis, we investigated the effects of LPA on isolated...

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Autores principales: Pamuklar, Zehra, Federico, Lorenzo, Liu, Shuying, Umezu-Goto, Makiko, Dong, Anping, Panchatcharam, Manikandan, Fulerson, Zachary, Berdyshev, Evgeny, Natarajan, Viswanathan, Fang, Xianjun, van Meeteren, Laurens A., Moolenaar, Wouter H., Mills, Gordon B., Morris, Andrew J., Smyth, Susan S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652269/
https://ncbi.nlm.nih.gov/pubmed/19139100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807820200
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