Autotaxin/Lysopholipase D and Lysophosphatidic Acid Regulate Murine Hemostasis and Thrombosis

The lipid mediator lysophosphatidic acid (LPA) is a potent regulator of vascular cell function in vitro, but its physiologic role in the cardiovasculature is largely unexplored. To address the role of LPA in regulating platelet function and thrombosis, we investigated the effects of LPA on isolated...

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Main Authors: Pamuklar, Zehra, Federico, Lorenzo, Liu, Shuying, Umezu-Goto, Makiko, Dong, Anping, Panchatcharam, Manikandan, Fulerson, Zachary, Berdyshev, Evgeny, Natarajan, Viswanathan, Fang, Xianjun, van Meeteren, Laurens A., Moolenaar, Wouter H., Mills, Gordon B., Morris, Andrew J., Smyth, Susan S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652269/
https://ncbi.nlm.nih.gov/pubmed/19139100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807820200
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