Autotaxin/Lysopholipase D and Lysophosphatidic Acid Regulate Murine Hemostasis and Thrombosis

The lipid mediator lysophosphatidic acid (LPA) is a potent regulator of vascular cell function in vitro, but its physiologic role in the cardiovasculature is largely unexplored. To address the role of LPA in regulating platelet function and thrombosis, we investigated the effects of LPA on isolated...

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Auteurs principaux: Pamuklar, Zehra, Federico, Lorenzo, Liu, Shuying, Umezu-Goto, Makiko, Dong, Anping, Panchatcharam, Manikandan, Fulerson, Zachary, Berdyshev, Evgeny, Natarajan, Viswanathan, Fang, Xianjun, van Meeteren, Laurens A., Moolenaar, Wouter H., Mills, Gordon B., Morris, Andrew J., Smyth, Susan S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Lipids and Lipoproteins: Metabolism, Regulation, and Signaling
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652269/
https://ncbi.nlm.nih.gov/pubmed/19139100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807820200
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