Triple helix-forming oligonucleotides target psoralen adducts to specific chromosomal sequences in human cells.
The ability to target photochemical adducts to specific genomic DNA sequences in cells is useful for studying DNA repair and mutagenesis in intact cells, and also as a potential mode of gene-specific therapy. Triple helix-forming DNA oligonucleotides linked to psoralen (psoTFOs) were designed to del...
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| Publicado en: | Nucleic Acids Res |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.24.4734 |
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