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Triple helix-forming oligonucleotides target psoralen adducts to specific chromosomal sequences in human cells.

The ability to target photochemical adducts to specific genomic DNA sequences in cells is useful for studying DNA repair and mutagenesis in intact cells, and also as a potential mode of gene-specific therapy. Triple helix-forming DNA oligonucleotides linked to psoralen (psoTFOs) were designed to del...

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Bibliografske podrobnosti
Main Authors: Oh, D H, Hanawalt, P C
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC148773/
https://ncbi.nlm.nih.gov/pubmed/10572173
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