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Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

The tumor suppressor p53 can trigger cell death independently of its transcriptional activity through subcellular translocation and activation of proapoptotic Bcl-2 family members. The regulation of such activity of endogenous p53 in response to stress remains largely unknown. Here we show that nucl...

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Detalhes bibliográficos
Main Authors: You, Han, Yamamoto, Kazuo, Mak, Tak Wah
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482564/
https://ncbi.nlm.nih.gov/pubmed/16757565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600889103
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