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FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

Loss-of-function mutations of phosphatase/tensin homolog deleted on chromosome 10 (PTEN)-induced putative kinase 1 (Pink1) (also known as Park6) identified in familial forms of Parkinson's disease (PD) are associated with compromised mitochondrial function. Emerging data suggest that Pink1 is a...

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Bibliografiske detaljer
Main Authors: Mei, Yang, Zhang, Yiru, Yamamoto, Kazuo, Xie, Wei, Mak, Tak W., You, Han
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654023/
https://ncbi.nlm.nih.gov/pubmed/19276113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901104106
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