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Regulation of cell cycle progression by forkhead transcription factor FOXO3 through its binding partner DNA replication factor Cdt1

To ensure genome stability, DNA must be replicated once and only once during each cell cycle. Cdt1 is tightly regulated to make sure that cells do not rereplicate their DNA. Multiple regulatory mechanisms operate to ensure degradation of Cdt1 in S phase. However, little is known about the positive r...

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Detalhes bibliográficos
Main Authors: Zhang, Yiru, Xing, Yuqian, Zhang, Lei, Mei, Yang, Yamamoto, Kazuo, Mak, Tak W., You, Han
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326503/
https://ncbi.nlm.nih.gov/pubmed/22451935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203210109
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