FOXO3a-dependent regulation of Puma in response to cytokine/growth factor withdrawal

Puma is an essential mediator of p53-dependent and -independent apoptosis in vivo. In response to genotoxic stress, Puma is induced in a p53-dependent manner. However, the transcription factor driving Puma up-regulation in response to p53-independent apoptotic stimuli has yet to be identified. Here,...

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Hlavní autoři: You, Han, Pellegrini, Marc, Tsuchihara, Katsuya, Yamamoto, Kazuo, Hacker, Georg, Erlacher, Miriam, Villunger, Andreas, Mak, Tak W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2006
Témata:
Brief Definitive Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118330/
https://ncbi.nlm.nih.gov/pubmed/16801400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060353
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