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Checkpoint kinase 1 is essential for fetal and adult hematopoiesis
Checkpoint kinase 1 (CHK1) is critical for S‐phase fidelity and preventing premature mitotic entry in the presence of DNA damage. Tumor cells have developed a strong dependence on CHK1 for survival, and hence, this kinase has developed into a promising drug target. Chk1 deficiency in mice results in...
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| Publicado no: | EMBO Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6680171/ https://ncbi.nlm.nih.gov/pubmed/31379128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847026 |
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