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Possible pitfalls investigating cell death responses in genetically engineered mouse models and derived cell lines

Genetically engineered mouse models are frequently used to identify pathophysiological consequences of deregulated cell death. Targeting pro-apoptotic or anti-apoptotic proteins of the extrinsic or intrinsic apoptotic signalling cascade is state of the art since more than two decades. Such animal mo...

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Detalhes bibliográficos
Main Authors: Manzl, Claudia, Baumgartner, Florian, Peintner, Lukas, Schuler, Fabian, Villunger, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3693039/
https://ncbi.nlm.nih.gov/pubmed/23454286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.02.012
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