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Minor cell death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf

Pro-apoptotic Bcl-2 family members of the BH3-only subgroup are critical for the establishment and maintenance of tissue homeostasis and can mediate apoptotic cell death in response to developmental cues or exogenously induced forms of cell stress and damage. Based on biochemical experiments as well...

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Autores principales: Baumgartner, Florian, Wöss, Claudia, Pedit, Victoria, Tzankov, Alexandar, Labi, Verena, Villunger, Andreas
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428852/
https://ncbi.nlm.nih.gov/pubmed/22430207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.78
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