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Suppression of B cell lymphomagenesis by the BH3-only proteins Bmf and Bad

Oncogenic c-Myc is known to balance excessive proliferation by apoptosis that can be triggered by p53-dependent and p53-independent signaling networks. Here, we provide evidence that the “BH3-only” pro-apoptotic Bcl-2 family members Bmf and Bad are potent antagonists of c-Myc-driven B cell lymphomag...

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Detalhes bibliográficos
Main Authors: Frenzel, Anna, Labi, Verena, Chmelewskij, Waldemar, Ploner, Christian, Geley, Stephan, Fiegl, Heidelinde, Tzankov, Alexandar, Villunger, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272372/
https://ncbi.nlm.nih.gov/pubmed/19965635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-212670
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