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Requirement for the TIE family of receptor tyrosine kinases in adult but not fetal hematopoiesis

In mammals, the continuous production of hematopoietic cells (HCs) is sustained by a small number of hematopoietic stem cells (HSCs) residing in the bone marrow. Early HSC activity arises in the aorta-gonad mesonephros region, within cells localized to the ventral floor of the major blood vessels, s...

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Autors principals: Puri, Mira C., Bernstein, Alan
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC240690/
https://ncbi.nlm.nih.gov/pubmed/14530387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2133552100
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