Tumor Regression and Autoimmunity in Patients Treated With Cytotoxic T Lymphocyte–Associated Antigen 4 Blockade and Interleukin 2: A Phase I/II Study

BACKGROUND: Cytotoxic T lymphocyte–associated antigen (CTLA)-4 can inhibit T-cell responses and is involved in tolerance against self antigens. We previously reported autoimmune manifestations and objective cancer regressions in patients with metastatic melanoma treated with CTLA-4 blockade. The pos...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Maker, Ajay V., Phan, Giao Q., Attia, Peter, Yang, James C., Sherry, Richard M., Topalian, Suzanne L., Kammula, Udai S., Royal, Richard E., Haworth, Leah R., Levy, Catherine, Kleiner, David, Mavroukakis, Sharon A., Yellin, Michael, Rosenberg, Steven A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473970/
https://ncbi.nlm.nih.gov/pubmed/16283570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/ASO.2005.03.536
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia