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Cytotoxic T-Lymphocyte–Associated Antigen-4 Blockage Can Induce Autoimmune Hypophysitis in Patients With Metastatic Melanoma and Renal Cancer

Cytotoxic T-lymphocyte–associated antigen-4 (CTLA-4) is an immunoregulatory molecule expressed by activated T cells and resting CD4(+)CD25(+) T cells. In patients with advanced melanoma, our group reported that administration of anti-CTLA-4 antibody mediated objective cancer regression in 13% of pat...

詳細記述

保存先:
書誌詳細
主要な著者: Blansfield, Joseph A., Beck, Kimberly E., Tran, Khoi, Yang, James C., Hughes, Marybeth S., Kammula, Udai S., Royal, Richard E., Topalian, Suzanne L., Haworth, Leah R., Levy, Catherine, Rosenberg, Steven A., Sherry, Richard M.
フォーマット: Artigo
言語:Inglês
出版事項: 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154350/
https://ncbi.nlm.nih.gov/pubmed/16224277
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