Ipilimumab (Anti-CTLA4 Antibody) Causes Regression of Metastatic Renal Cell Cancer Associated With Enteritis and Hypophysitis

The inhibitory receptor CTLA4 has a key role in peripheral tolerance of T cells for both normal and tumor-associated antigens. Murine experiments suggested that blockade of CTLA4 might have antitumor activity and a clinical experience with the blocking antibody ipilimumab in patients with metastatic...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Yang, James C., Hughes, Marybeth, Kammula, Udai, Royal, Richard, Sherry, Richard M., Topalian, Suzanne L., Suri, Kimberly B., Levy, Catherine, Allen, Tamika, Mavroukakis, Sharon, Lowy, Israel, White, Donald E., Rosenberg, Steven A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134980/
https://ncbi.nlm.nih.gov/pubmed/18049334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318156e47e
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge