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Analysis of the Cellular Mechanism of Antitumor Responses and Autoimmunity in Patients Treated with CTLA-4 Blockade

We have demonstrated previously that the administration of CTLA-4 blockade has mediated objective cancer regression and autoimmunity in patients with metastatic melanoma. To explore the mechanism of these in vivo effects, we have studied the changes in lymphocyte phenotype and function in patients r...

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Autores principales: Maker, Ajay V., Attia, Peter, Rosenberg, Steven A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1473972/
https://ncbi.nlm.nih.gov/pubmed/16301685
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