Robust antitumor responses result from local chemotherapy and CTLA-4 blockade

Clinical responses to immunotherapy have been associated with augmentation of preexisting immune responses, manifested by heightened inflammation in the tumor microenvironment. However, many tumors have a non-inflamed microenvironment, and response rates to immunotherapy in melanoma have been <50...

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Publicado no:Cancer Immunol Res
Main Authors: Ariyan, Charlotte E., Brady, Mary Sue., Siegelbaum, Robert H., Hu, Jian, Bello, Danielle M., Green, Jamie, Fisher, Charles, Lefkowitz, Robert A., Panageas, Kathleen S., Pulitzer, Melissa, Vignali, Marissa, Emerson, Ryan, Tipton, Christopher, Robins, Harlan, Merghoub, Taha, Yuan, Jianda, Jungbluth, Achim, Blando, Jorge, Sharma, Padmanee, Rudensky, Alexander Y., Wolchok, Jedd D., Allison, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6857638/
https://ncbi.nlm.nih.gov/pubmed/29339377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0356
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