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Runaway domain swapping in amyloid-like fibrils of T7 endonuclease I

Amyloid fibrils are associated with >20 fatal human disorders, including Alzheimer's, Parkinson's, and prion diseases. Knowledge of how soluble proteins assemble into amyloid fibrils remains elusive despite its potential usefulness for developing diagnostics and therapeutics. In at leas...

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書目詳細資料
Main Authors: Guo, Zhefeng, Eisenberg, David
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472426/
https://ncbi.nlm.nih.gov/pubmed/16698921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602607103
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