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Domain swapping and amyloid fibril conformation

For several different proteins an apparent correlation has been observed between the propensity for dimerization by domain-swapping and the ability to aggregate into amyloid-like fibrils. Examples include the disease-related proteins β(2)-microglobulin and transthyretin. This has led to proposals th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: van der Wel, Patrick C.A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399535/
https://ncbi.nlm.nih.gov/pubmed/22437737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.18987
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