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Structural Characterization of GNNQQNY Amyloid Fibrils by Magic Angle Spinning NMR.

Several human diseases are associated with the formation of amyloid aggregates, but experimental characterization of these amyloid fibrils and their oligomeric precursors has remained challenging. Experimental and computational analysis of simpler model systems has therefore been necessary, for inst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: van der Wel, Patrick C.A., Lewandowski, Józef R., Griffin, Robert G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026921/
https://ncbi.nlm.nih.gov/pubmed/20695483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100077x
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