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Structural Characterization of GNNQQNY Amyloid Fibrils by Magic Angle Spinning NMR.

Several human diseases are associated with the formation of amyloid aggregates, but experimental characterization of these amyloid fibrils and their oligomeric precursors has remained challenging. Experimental and computational analysis of simpler model systems has therefore been necessary, for inst...

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Detalhes bibliográficos
Main Authors: van der Wel, Patrick C.A., Lewandowski, Józef R., Griffin, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026921/
https://ncbi.nlm.nih.gov/pubmed/20695483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100077x
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