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Accurate Determination of Interstrand Distances and Alignment in Amyloid Fibrils by Magic Angle Spinning NMR

Amyloid fibrils are structurally ordered aggregates of proteins whose formation is associated with many neurodegenerative and other diseases. For that reason, their high resolution structures are of considerable interest and have been studied using a wide range of techniques, notably electron micros...

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Detalhes bibliográficos
Main Authors: Caporini, Marc A., Bajaj, Vikram S., Veshtort, Mikhail, Fitzpatrick, Anthony, MacPhee, Cait E, Vendruscolo, Michele, Dobson, Christopher M., Griffin, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959142/
https://ncbi.nlm.nih.gov/pubmed/20925357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp106675h
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