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Accurate Determination of Interstrand Distances and Alignment in Amyloid Fibrils by Magic Angle Spinning NMR

Amyloid fibrils are structurally ordered aggregates of proteins whose formation is associated with many neurodegenerative and other diseases. For that reason, their high resolution structures are of considerable interest and have been studied using a wide range of techniques, notably electron micros...

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Autors principals: Caporini, Marc A., Bajaj, Vikram S., Veshtort, Mikhail, Fitzpatrick, Anthony, MacPhee, Cait E, Vendruscolo, Michele, Dobson, Christopher M., Griffin, Robert G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2959142/
https://ncbi.nlm.nih.gov/pubmed/20925357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp106675h
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