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Runaway domain swapping in amyloid-like fibrils of T7 endonuclease I

Amyloid fibrils are associated with >20 fatal human disorders, including Alzheimer's, Parkinson's, and prion diseases. Knowledge of how soluble proteins assemble into amyloid fibrils remains elusive despite its potential usefulness for developing diagnostics and therapeutics. In at leas...

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Detalhes bibliográficos
Main Authors: Guo, Zhefeng, Eisenberg, David
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472426/
https://ncbi.nlm.nih.gov/pubmed/16698921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602607103
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