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β(2)-microglobulin forms 3D domain-swapped amyloid fibrils with disulfide linkages
β(2)-microglobulin (β(2)m) is the light chain of type I major histocompatibility complex. It deposits as amyloid fibrils within joints during long-term hemodialysis treatment. Despite the devastating effects of dialysis-related amyloidosis, full understanding of how fibrils form from soluble β(2)m r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3058263/ https://ncbi.nlm.nih.gov/pubmed/21131979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1948 |
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