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An amyloid-forming segment of β2-microglobulin suggests a molecular model for the fibril

In humans suffering from dialysis-related amyloidosis, the protein β2-microglobulin (β2M) is deposited as an amyloid; however, an amyloid of β2M is unknown in mice. β2M sequences from human and mouse are 70% identical, but there is a seven-residue peptide in which six residues differ. This peptide f...

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מידע ביבליוגרפי
Main Authors: Ivanova, Magdalena I., Sawaya, Michael R., Gingery, Mari, Attinger, Antoine, Eisenberg, David
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC489978/
https://ncbi.nlm.nih.gov/pubmed/15249659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403756101
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