Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation

Notch signaling promotes commitment of keratinocytes to differentiation and suppresses tumorigenesis. p63, a p53 family member, has been implicated in establishment of the keratinocyte cell fate and/or maintenance of epithelial self-renewal. Here we show that p63 expression is suppressed by Notch1 a...

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Main Authors: Nguyen, Bach-Cuc, Lefort, Karine, Mandinova, Anna, Antonini, Dario, Devgan, Vikram, Della Gatta, Giusy, Koster, Maranke I., Zhang, Zhuo, Wang, Jian, di Vignano, Alice Tommasi, Kitajewski, Jan, Chiorino, Giovanna, Roop, Dennis R., Missero, Caterina, Dotto, G. Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472299/
https://ncbi.nlm.nih.gov/pubmed/16618808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1406006
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