Direct targets of the TRP63 transcription factor revealed by a combination of gene expression profiling and reverse engineering

Genome-wide identification of bona-fide targets of transcription factors in mammalian cells is still a challenge. We present a novel integrated computational and experimental approach to identify direct targets of a transcription factor. This consists of measuring time-course (dynamic) gene expressi...

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Main Authors: Della Gatta, Giusy, Bansal, Mukesh, Ambesi-Impiombato, Alberto, Antonini, Dario, Missero, Caterina, di Bernardo, Diego
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2008
Teme:
Methods
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413161/
https://ncbi.nlm.nih.gov/pubmed/18441228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.073601.107
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