Crystal Structure of the Simian Virus 40 Large T-Antigen Origin-Binding Domain

The origins of replication of DNA tumor viruses have a highly conserved feature, namely, multiple binding sites for their respective initiator proteins arranged as inverted repeats. In the 1.45-Å crystal structure of the simian virus 40 large T-antigen (T-ag) origin-binding domain (obd) reported her...

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Main Authors: Meinke, Gretchen, Bullock, Peter A., Bohm, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472039/
https://ncbi.nlm.nih.gov/pubmed/16611889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.9.4304-4312.2006
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