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The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA

DNA replication is initiated upon binding of “initiators” to origins of replication. In simian virus 40 (SV40), the core origin contains four pentanucleotide binding sites organized as pairs of inverted repeats. Here we describe the crystal structures of the origin binding domain (obd) of the SV40 l...

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Autores principales: Meinke, Gretchen, Phelan, Paul, Moine, Stephanie, Bochkareva, Elena, Bochkarev, Alexey, Bullock, Peter A, Bohm, Andrew
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779811/
https://ncbi.nlm.nih.gov/pubmed/17253903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050023
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