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Structure of the origin-binding domain of simian virus 40 large T antigen bound to DNA
The large T antigen (T-ag) protein binds to and activates DNA replication from the origin of DNA replication (ori) in simian virus 40 (SV40). Here, we determined the crystal structures of the T-ag origin-binding domain (OBD) in apo form, and bound to either a 17 bp palindrome (sites 1 and 3) or a 23...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698898/ https://ncbi.nlm.nih.gov/pubmed/17139255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601452 |
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