The Origin DNA-Binding and Single-Stranded DNA-Binding Domains of Simian Virus 40 Large T Antigen Are Distinct

Little is known about the ability of simian virus 40 (SV40) T antigen to bind single-stranded DNA. We demonstrate here that a mutant (259-708) missing the first 258 amino acids of T antigen and its origin-binding domain bound single-stranded DNA at close to normal levels, whereas a mutant containing...

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Hlavní autoři: Wu, Chunxiao, Edgil, Dianna, Simmons, Daniel T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Animal Viruses
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110609/
https://ncbi.nlm.nih.gov/pubmed/9811771
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