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The Origin DNA-Binding and Single-Stranded DNA-Binding Domains of Simian Virus 40 Large T Antigen Are Distinct

Little is known about the ability of simian virus 40 (SV40) T antigen to bind single-stranded DNA. We demonstrate here that a mutant (259-708) missing the first 258 amino acids of T antigen and its origin-binding domain bound single-stranded DNA at close to normal levels, whereas a mutant containing...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Wu, Chunxiao, Edgil, Dianna, Simmons, Daniel T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110609/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811771/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.10256-10259.1998
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