The Origin DNA-Binding and Single-Stranded DNA-Binding Domains of Simian Virus 40 Large T Antigen Are Distinct

Little is known about the ability of simian virus 40 (SV40) T antigen to bind single-stranded DNA. We demonstrate here that a mutant (259-708) missing the first 258 amino acids of T antigen and its origin-binding domain bound single-stranded DNA at close to normal levels, whereas a mutant containing...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Wu, Chunxiao, Edgil, Dianna, Simmons, Daniel T.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Animal Viruses
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110609/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.10256-10259.1998
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