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The Crystal Structure of the SV40 T-Antigen Origin Binding Domain in Complex with DNA

DNA replication is initiated upon binding of “initiators” to origins of replication. In simian virus 40 (SV40), the core origin contains four pentanucleotide binding sites organized as pairs of inverted repeats. Here we describe the crystal structures of the origin binding domain (obd) of the SV40 l...

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Détails bibliographiques
Auteurs principaux: Meinke, Gretchen, Phelan, Paul, Moine, Stephanie, Bochkareva, Elena, Bochkarev, Alexey, Bullock, Peter A, Bohm, Andrew
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779811/
https://ncbi.nlm.nih.gov/pubmed/17253903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050023
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